If the same user account does not have the issue on a separate PC then we know the problem is isolated to that user profile. Open Control Panel (Start>Settings>Control Panel) Removing the user profile and re-creating the user profile is a pretty big step just for a lost email signature but it's the last resort. As a first step in troubleshooting email delivery problems for Microsoft 365 for business, we recommend that you download and run Support and Recovery Assistant on the affected computer. Select the Reinstall or Repair button, click Next.Ĭlick Install and follow any prompts provided by the repair tool. Notice that if you're experiencing issues that affect Outlook for Mac or are having mobile access issues, you can use the app to check your account settings.